Rekombinanter IDH1 Antikörper (AA 281-414)
Kurzübersicht für Rekombinanter IDH1 Antikörper (AA 281-414) (ABIN7873286)
Target
Alle IDH1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 281-414
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Verwendungszweck
- IDH1 Antibody / Isocitrate Dehydrogenase (R132H mutant) (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 281-414 was used as the immunogen for the IDH1 R132H antibody.
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Isotyp
- IgG, kappa
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anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) antibody
IDH1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 74-333) antibodyIDH1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibodyIDH1 Reaktivität: Human, Maus, Affe WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 7G8A1 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibodyIDH1 Reaktivität: Human, Maus WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB18238 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 381-413), (C-Term) antibodyIDH1 Reaktivität: Human, Maus, Ratte WB, IHC, FACS, IF, ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibodyIDH1 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 4A4A8 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (Center) antibodyIDH1 Reaktivität: Human, Maus WB, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (N-Term) antibodyIDH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibodyIDH1 Reaktivität: Human, Maus WB, IHC, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 63-90) antibodyIDH1 Reaktivität: Human, Maus WB, IHC, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the IDH1 R132H antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the IDH1 R132H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
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Andere Bezeichnung
- IDH1
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Hintergrund
- IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorigenesis. IDH1 R132H can be used as a diagnostic marker to help differentiate infiltrating gliomas from gliosis, and as a prognostic marker for gliomas and secondary glioblastoma multiforme. IDH1 R132H antibody shows strong cytoplasmic staining and weaker nuclear staining in tumor cells with the R132H-mutated peptide. Diffuse staining of the fibrillary tumor matrix is also seen.
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UniProt
- O75874
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Pathways
- Warburg Effekt
Target
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