TTC8 Antikörper (AA 271-533)

Produktnummer ABIN7873159

Der Kaninchen Polyklonal anti-TTC8 Antikörper (ABIN7873159) detektiert spezifisch TTC8 in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TTC8 Antikörper (AA 271-533) (ABIN7873159)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TTC8 Antikörper

Bindungsspezifität: AA 271-533

Verwendungszweck: BBS8 Antibody / Bardet-Biedl syndrome 8 / TTC8

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E271-Q533) was used as the immunogen for the BBS8 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the BBS8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the BBS8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Andere Bezeichnung: BBS8

Hintergrund: Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 (BBS8) is a protein that in humans is encoded by the TTC8 gene. This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

UniProt: Q8TAM2

Pathways: Hedgehog Signalweg