IL-11 Antikörper (AA 27-61)
Kurzübersicht für IL-11 Antikörper (AA 27-61) (ABIN7873137)
Target
Alle IL-11 (IL11) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 27-61
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Verwendungszweck
- IL-11 Antibody (N-Terminal Region)
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 27-61 from human IL-11 was used as the immunogen for the IL-11 antibody.
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Isotyp
- Ig Fraction
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 Reaktivität: Human WB, ELISA, Neut Wirt: Kaninchen Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the IL-11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the IL-11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-11 (IL11) (Interleukin 11 (IL11))
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Andere Bezeichnung
- IL-11
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Hintergrund
- Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href=http://www.uniprot.org/citations/12919066 target=_blank>12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt]
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UniProt
- P20809
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Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
Target
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