Rekombinanter IL3RA Antikörper (AA 26-171)

Produktnummer ABIN7872984

Der Maus Monoklonal anti-IL3RA Antikörper wird verwendet zum Nachweis von IL3RA in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter IL3RA Antikörper (AA 26-171) (ABIN7872984)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RIL3RA-9212

Produktdetails anti-IL3RA Antikörper

Bindungsspezifität: AA 26-171

Verwendungszweck: Recombinant IL3RA Antibody / Interleukin 3 Receptor alpha / CD123

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human IL3RA protein (within amino acids 26-171) was used as the immunogen for the recombinant IL3RA antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant IL3RA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant IL3RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: IL3RA

Hintergrund: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

UniProt: P26951

Pathways: JAK-STAT Signalweg