Rekombinanter ADRP Antikörper (AA 249-376)

Produktnummer ABIN7872821

Dieser Maus Monoklonal Antikörper detektiert spezifisch ADRP in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter ADRP Antikörper (AA 249-376) (ABIN7872821)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADRP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RADFP-9321

Produktdetails anti-ADRP Antikörper

Bindungsspezifität: AA 249-376

Verwendungszweck: Adipose differentiation-related protein Antibody / ADRP / Adipophilin / Perilipin 2

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 249-376) of human Adipophilin protein was used as the immunogen for the Adipose differentiation-related protein antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Adipose differentiation-related protein antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Adipose differentiation-related protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Andere Bezeichnung: Adipose differentiation-related protein

Hintergrund: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism