GCLM Antikörper (AA 246-274)
Kurzübersicht für GCLM Antikörper (AA 246-274) (ABIN7872786)
Target
Alle GCLM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 246-274
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Verwendungszweck
- GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 246-274 from the human protein were used as the immunogen for the GCLM antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the GCLM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the GCLM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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Andere Bezeichnung
- GCLM
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Hintergrund
- GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
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UniProt
- P48507
Target
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