ATR Antikörper (AA 24-1324)

Produktnummer ABIN7872663

Der Kaninchen Polyklonal anti-ATR Antikörper wird verwendet zum Nachweis von ATR in Proben von Human. Er wurde validiert für ELISA und IF.

Kurzübersicht für ATR Antikörper (AA 24-1324) (ABIN7872663)

Target: ATR (ATR serine/threonine kinase (ATR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATR Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-ATR Antikörper

Bindungsspezifität: AA 24-1324

Verwendungszweck: ATR Antibody / Ataxia telangiectasia and Rad3-related protein / FRP1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E24-D1324) was used as the immunogen for the ATR antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ATR antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ATR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ATR

Target: ATR (ATR serine/threonine kinase (ATR))

Andere Bezeichnung: ATR

Hintergrund: Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus