APOA4 Antikörper (AA 239-371)

Produktnummer ABIN7872646

Der Maus Monoklonal anti-APOA4 Antikörper (Klon APOA4-3372) (ABIN7872646) detektiert spezifisch APOA4 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für APOA4 Antikörper (AA 239-371) (ABIN7872646)

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOA4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: APOA4-3372

Produktdetails anti-APOA4 Antikörper

Bindungsspezifität: AA 239-371

Verwendungszweck: APOAIV Antibody / Apolipoprotein A4

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 239-371 from the human protein was used as the immunogen for the APOAIV antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the APOAIV antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the APOAIV antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu APOA4

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Andere Bezeichnung: APOAIV

Hintergrund: Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

UniProt: P06727

Pathways: Lipid Metabolism