Rekombinanter Inhibin alpha Antikörper (AA 233-362)

Produktnummer ABIN7872598

Der Kaninchen Monoklonal anti-Inhibin alpha Antikörper (Klon INHA-8872R) (ABIN7872598) detektiert spezifisch Inhibin alpha in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Inhibin alpha Antikörper (AA 233-362) (ABIN7872598)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Inhibin alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: INHA-8872R

Produktdetails anti-Inhibin alpha Antikörper

Bindungsspezifität: AA 233-362

Verwendungszweck: Inhibin alpha Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human Inhibin alpha protein (within amino acids 233-362) was used as the immunogen for the Inhibin alpha antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Inhibin alpha antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Inhibin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Andere Bezeichnung: Inhibin alpha

Hintergrund: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same Alpha subunit, covalently linked to 1 of 2 distinct subunits, beta-Alpha or beta-beta. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor beta (TFGbeta) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion