ILF2 Antikörper (AA 23-356)

Produktnummer ABIN7872527

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ILF2 in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für ILF2 Antikörper (AA 23-356) (ABIN7872527)

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ILF2 Antikörper

Bindungsspezifität: AA 23-356

Verwendungszweck: Zebrafish ILF2 Antibody / Interleukin enhancer-binding factor 2 / NF45

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish NF45/ILF2 recombinant protein (amino acids Y23-K356) was used as the immunogen for the Zebrafish ILF2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish ILF2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish ILF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ILF2

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Andere Bezeichnung: ILF2

Hintergrund: Interleukin enhancer-binding factor 2, also called 'Nuclear factor of activated T-cells 45 kDa,' is a protein that in humans is encoded by the ILF2 gene. The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

UniProt: Q6NZ06