ILF2 Antikörper (N-Term)

Produktnummer ABIN1881458

Produktdetails anti-ILF2 Antikörper

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Bindungsspezifität: AA 84-112, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ILF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-112 amino acids from the N-terminal region of human ILF2.

Klon: RB42341

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ILF2 Antikörper (ABIN1881458)

Karmakar, Mahajan, Schulz, Boyapaty, Weissman: "A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus." in: The EMBO journal, Vol. 29, Issue 19, pp. 3260-71, (2010) (PubMed).

Graber, Baird, Kao, Mathews, Holcik: "NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response." in: Cell death and differentiation, Vol. 17, Issue 4, pp. 719-29, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Kiesler, Haynes, Shi, Kao, Wysocki, Vercelli: "NF45 and NF90 regulate HS4-dependent interleukin-13 transcription in T cells." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8256-67, (2010) (PubMed).

Sakamoto, Aoki, Higuchi, Todaka, Morisawa, Tamaki, Hatano, Fukushima, Taniguchi, Agata: "The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3754-69, (2009) (PubMed).

Details zu ILF2

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Andere Bezeichnung: ILF2 (ILF2 Produkte)

Synonyme: nf45 antikoerper, pro3063 antikoerper, ILF2 antikoerper, wu:fb34h01 antikoerper, zgc:73084 antikoerper, zgc:77276 antikoerper, NF45 antikoerper, PRO3063 antikoerper, 6230405A16Rik antikoerper, TEG-267 antikoerper, Tex261 antikoerper, Tex267 antikoerper, interleukin enhancer binding factor 2 antikoerper, interleukin enhancer binding factor 2 L homeolog antikoerper, ilf2 antikoerper, ILF2 antikoerper, ilf2.L antikoerper, Ilf2 antikoerper

Hintergrund: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.

Molekulargewicht: 43062

NCBI Accession: NP_001254738, NP_004506

UniProt: Q12905