Retinoid X Receptor alpha Antikörper (AA 226-462)

Produktnummer ABIN7872411

Der Maus Monoklonal anti-Retinoid X Receptor alpha Antikörper wird verwendet zum Nachweis von Retinoid X Receptor alpha in Proben von Human, Maus und Ratte. Er wurde validiert für WB und FACS.

Kurzübersicht für Retinoid X Receptor alpha Antikörper (AA 226-462) (ABIN7872411)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: 5E7-

Produktdetails anti-Retinoid X Receptor alpha Antikörper

Bindungsspezifität: AA 226-462

Verwendungszweck: Retinoid X Receptor alpha Antibody / RXRA

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids A226-T462) was used as the immunogen for the Retinoid X Receptor alpha antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Retinoid X Receptor alpha antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Retinoid X Receptor alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Andere Bezeichnung: Retinoid X Receptor alpha

Hintergrund: Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded by the RXRA gene. Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C