Retinoid X Receptor alpha Antikörper (N-Term)

Produktnummer ABIN2778244

Produktdetails anti-Retinoid X Receptor alpha Antikörper

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoid X Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GPGIGSPGQL HSPISTLSSP INGMGPPFSV ISSPMGPHSM SVPTTPTLGF

Homologie: Cow: 100%, Dog: 78%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 78%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RXRA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RXRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 462 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Andere Bezeichnung: RXRA (RXRA Produkte)

Synonyme: NR2B1 antikoerper, 9530071D11Rik antikoerper, Nr2b1 antikoerper, RXRalpha1 antikoerper, RXRalpha antikoerper, rxra-A antikoerper, xRXR alpha antikoerper, xrxra antikoerper, RXRA antikoerper, RXR alpha antikoerper, etID309731.5 antikoerper, rxr antikoerper, rxra antikoerper, rxrg antikoerper, RXRalpha-B antikoerper, retinoid X receptor alpha antikoerper, retinoid X receptor alpha L homeolog antikoerper, retinoid x receptor, alpha b antikoerper, retinoid X receptor, alpha a antikoerper, RXRA antikoerper, Rxra antikoerper, rxra.L antikoerper, CpipJ_CPIJ010249 antikoerper, rxrab antikoerper, rxraa antikoerper

Hintergrund: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ16020, FLJ16733, MGC102720, NR2B1
Protein Interaction Partner: PPARG, VDR, NCOA1, NSD1, UBC, NR1I3, NCOA4, THRB, THRA, ALOX15B, RARA, PPARA, CHD9, PRKD2, NR0B2, STAT1, NR3C2, SMAD2, GK, JAZF1, ACVR1B, NR1I2, NCOA2, PSMC5, RAD54L2, ARID5A, PML, SUMO1, ESR2, ESR1, BHLHE40, BHLHE41, NR4A1, EP300, NCOR1, NCOA6, NCOA3, TR
Protein Size: 462

Molekulargewicht: 51 kDa

Gen-ID: 6256

NCBI Accession: NM_002957, NP_002948

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C