Retinoid X Receptor alpha Antikörper (N-Term)

Produktnummer ABIN2778244

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Retinoid X Receptor alpha in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Meerschweinchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für Retinoid X Receptor alpha Antikörper (N-Term) (ABIN2778244)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoid X Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Retinoid X Receptor alpha Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RXRA Antibody - N-terminal region

Sequenz: GPGIGSPGQL HSPISTLSSP INGMGPPFSV ISSPMGPHSM SVPTTPTLGF

Homologie: Cow: 100%, Dog: 78%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 78%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RXRA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RXRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34060-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Andere Bezeichnung: RXRA

Hintergrund:

Background Information: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Retinoid X receptor, alpha

Alternative Symbols: NR2B1

Protein Name: Retinoic acid receptor RXR-alpha

Molekulargewicht: 51kDa

Gen-ID: 6256

NCBI Accession: NP_002948

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C