MID1 Antikörper (AA 226-278)

Produktnummer ABIN7872405

Der Kaninchen Polyklonal anti-MID1 Antikörper wird verwendet zum Nachweis von MID1 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für MID1 Antikörper (AA 226-278) (ABIN7872405)

Target: MID1 (Midline 1 (MID1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MID1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-MID1 Antikörper

Bindungsspezifität: AA 226-278

Verwendungszweck: MID1 Antibody

Aufreinigung: Affinity purified

Immunogen: Amino acids N226-Q278 from the human protein were used as the immunogen for the MID1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MID1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: Store the MID1 antibody at -20oC.

Details zu MID1

Target: MID1 (Midline 1 (MID1))

Andere Bezeichnung: MID1

Hintergrund: Midline-1 is a protein found in humans that is encoded by the MID1 gene. The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

UniProt: O15344