LGI4 Antikörper (AA 225-531)

Produktnummer ABIN7872402

Der Kaninchen Polyklonal anti-LGI4 Antikörper wird verwendet zum Nachweis von LGI4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC (p), FACS und IF.

Kurzübersicht für LGI4 Antikörper (AA 225-531) (ABIN7872402)

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-LGI4 Antikörper

Bindungsspezifität: AA 225-531

Verwendungszweck: LGI4 Antibody / Leucine-rich repeat LGI family member 4

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids E225-H531) was used as the immunogen for the LGI4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LGI4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the LGI4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LGI4

Target: LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))

Andere Bezeichnung: LGI4

Hintergrund: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs). Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with autodominant lateral temporal epilepsy (ADTLE). However, the LGI4 gene is located in a region linked to benign familial infantile convulsions and a GC-to-AT polymorphism in LGI4 was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.

UniProt: Q8N135