FGFR2 Antikörper (AA 22-368)

Produktnummer ABIN7872321

Der Kaninchen Polyklonal anti-FGFR2 Antikörper wird verwendet zum Nachweis von FGFR2 in Proben von Human. Er wurde validiert für WB, ELISA, FACS und IHC (p).

Kurzübersicht für FGFR2 Antikörper (AA 22-368) (ABIN7872321)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FGFR2 Antikörper

Bindungsspezifität: AA 22-368

Verwendungszweck: FGFR2 Antibody / Fibroblast growth factor receptor 2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R22-E368) was used as the immunogen for the FGFR2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FGFR2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the FGFR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Andere Bezeichnung: FGFR2

Hintergrund: Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.

UniProt: P21802

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding