Rekombinanter Decorin Antikörper (AA 212-336)

Produktnummer ABIN7872201

Der Kaninchen Monoklonal anti-Decorin Antikörper wird verwendet zum Nachweis von Decorin in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter Decorin Antikörper (AA 212-336) (ABIN7872201)

Target: Decorin (DCN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: DCN-7031R

Produktdetails anti-Decorin Antikörper

Bindungsspezifität: AA 212-336

Verwendungszweck: DCN Antibody / Decorin (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 212-336 was used as the immunogen for the DCN antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DCN antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DCN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: DCN

Hintergrund: Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process