Neuregulin 1 Antikörper (AA 21-242)

Produktnummer ABIN7872151

Der Maus Monoklonal anti-Neuregulin 1 Antikörper (Klon NRG1-2710) (ABIN7872151) detektiert spezifisch Neuregulin 1 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Neuregulin 1 Antikörper (AA 21-242) (ABIN7872151)

Target: Neuregulin 1 (NRG1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuregulin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: NRG1-2710

Produktdetails anti-Neuregulin 1 Antikörper

Bindungsspezifität: AA 21-242

Verwendungszweck: Neuregulin-1 Antibody / NRG1

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the Neuregulin-1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Neuregulin-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Neuregulin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Neuregulin 1

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: Neuregulin-1

Hintergrund: Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

UniProt: Q02297

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation