Der Maus Monoklonal anti-Thrombospondin 1 Antikörper wird verwendet zum Nachweis von Thrombospondin 1 in Proben von Human. Er wurde validiert für ELISA und IHC (p).
Thrombospondin-1 Antibody / THBS1 (azide and preservative free)
Aufreinigung
Protein A/G affinity
Immunogen
A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Thrombospondin-1 antibody.
Optimal dilution of the Thrombospondin-1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Thrombospondin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
Thrombospondin 1 (THBS1)
Andere Bezeichnung
Thrombospondin-1
Hintergrund
The thrombospondin proteins (TSP 1-4) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell surface proteins form complexes of both homo- and heteromultimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells, and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1 and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.