Aquaporin 4 Antikörper (AA 200-323)

Produktnummer ABIN7871962

Der Maus Monoklonal anti-Aquaporin 4 Antikörper (Klon AQP4-3322) (ABIN7871962) detektiert spezifisch Aquaporin 4 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Aquaporin 4 Antikörper (AA 200-323) (ABIN7871962)

Target: Aquaporin 4 (AQP4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aquaporin 4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: AQP4-3322

Produktdetails anti-Aquaporin 4 Antikörper

Bindungsspezifität: AA 200-323

Verwendungszweck: AQP4 Antibody / Aquaporin 4 (azide and preservative free)

Aufreinigung: Protein G affinity

Immunogen: A human partial recombinant protein (from within amino acids 200-323) was used as the immunogen for the AQP4 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AQP4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot the AQP4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Aquaporin 4

Target: Aquaporin 4 (AQP4)

Andere Bezeichnung: AQP4

Hintergrund: In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

UniProt: P55087

Pathways: Sensory Perception of Sound