Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Aquaporin 4 Antikörper (C-Term)

AQP4 Reaktivität: Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN863209
  • Target Alle Aquaporin 4 (AQP4) Antikörper anzeigen
    Aquaporin 4 (AQP4)
    Bindungsspezifität
    • 20
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 65
    • 58
    • 58
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 73
    • 18
    • 1
    Kaninchen
    Klonalität
    • 72
    • 20
    Polyklonal
    Konjugat
    • 48
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aquaporin 4 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 46
    • 25
    • 25
    • 21
    • 15
    • 14
    • 14
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~35 kDa. May detect larger glycosylated bands ~50 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein A Purified
    Immunogen
    Produced against the C-terminal peptide (Sequence N-CTKGSYMEVEDNRSQVETED) of rat aquaporin 4
    Top Product
    Discover our top product AQP4 Primärantikörper
  • Applikationshinweise
    • WB (1:2000)
    • IHC (1:200)
    • ICC/IF (1:400)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    0.5 μg/ml of ABIN863209 was sufficient for detection of aquaporin 4 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Gatto, Amin, Deyoung, Hey, Mareci, Magin: "Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice." in: Translational neurodegeneration, Vol. 7, pp. 20, (2018) (PubMed).

  • Target
    Aquaporin 4 (AQP4)
    Andere Bezeichnung
    Aquaporin 4 (AQP4 Produkte)
    Synonyme
    zgc:100922 antikoerper, si:ch211-192k9.1 antikoerper, AQP4 antikoerper, LOC100232616 antikoerper, HMIWC2 antikoerper, MIWC antikoerper, WCH4 antikoerper, AQP-4 antikoerper, AQP4.M23 antikoerper, MIWC2 antikoerper, Miwc antikoerper, aquaporin-4 antikoerper, aquaporin 4 antikoerper, aquaporin 4 L homeolog antikoerper, aqp4 antikoerper, AQP4 antikoerper, aqp4.L antikoerper, Aqp4 antikoerper
    Hintergrund
    Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 4 is constitutively expressed in the basolateral cell membrane of principal collecting duct cells in the kidney and provide a pathway for water to exit these cells (3). It is also expressed in astrocytes and is up regulated by direct insult to the CNS (4). Aquaporin 4 has been proposed as the primary autoimmune target in neuromyelitis optica ( 5, 6).
    Gen-ID
    25293
    NCBI Accession
    NP_036957
    UniProt
    P47863
    Pathways
    Sensory Perception of Sound
Sie sind hier:
Kundenservice