TMEM255B Antikörper (AA 196-240)

Produktnummer ABIN7871709

Der Kaninchen Polyklonal anti-TMEM255B Antikörper wird verwendet zum Nachweis von TMEM255B in Proben von Maus und Ratte. Er wurde validiert für ELISA, WB und IHC (p).

Kurzübersicht für TMEM255B Antikörper (AA 196-240) (ABIN7871709)

Target: TMEM255B (Transmembrane Protein 255B (TMEM255B))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM255B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TMEM255B Antikörper

Bindungsspezifität: AA 196-240

Verwendungszweck: Fam70b Antibody / Tmem255b

Aufreinigung: Affinity purified

Immunogen: Recombinant mouse protein (amino acids Q196-L240) was used as the immunogen for the Fam70b antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Fam70b antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Fam70b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TMEM255B

Target: TMEM255B (Transmembrane Protein 255B (TMEM255B))

Andere Bezeichnung: Fam70b

Hintergrund: FAM70B (family with sequence similarity 70, member B) is a 326 amino acid membrane protein that belongs to the FAM70 family. The gene that encodes FAM70B maps to human chromosome 13, which contains around 114 million base pairs and encodes roughly 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

UniProt: Q5FW56