ERCC1 Antikörper (AA 191-281)

Produktnummer ABIN7871657

Dieser Maus Monoklonal Antikörper detektiert spezifisch ERCC1 in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ERCC1 Antikörper (AA 191-281) (ABIN7871657)

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERCC1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: ERCC1-2683

Produktdetails anti-ERCC1 Antikörper

Bindungsspezifität: AA 191-281

Verwendungszweck: ERCC1 Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 191-281 was used as the immunogen for the ERCC1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ERCC1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ERCC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Andere Bezeichnung: ERCC1

Hintergrund: Excision Repair Cross Complementing 1 (ERCC1) is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.

UniProt: P07992

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response