STING/TMEM173 Antikörper (AA 190-290)

Produktnummer ABIN7871640

Der Maus Monoklonal anti-STING/TMEM173 Antikörper wird verwendet zum Nachweis von STING/TMEM173 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für STING/TMEM173 Antikörper (AA 190-290) (ABIN7871640)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser STING/TMEM173 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: STING1-7434

Produktdetails anti-STING/TMEM173 Antikörper

Bindungsspezifität: AA 190-290

Verwendungszweck: Stimulator of interferon genes protein Antibody / STING1 / TMEM17 / ERIS / MITA (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the Stimulator of interferon genes protein antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Stimulator of interferon genes protein antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Stimulator of interferon genes protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Andere Bezeichnung: Stimulator of interferon genes protein

Hintergrund: TMEM173 (transmembrane protein 173), also called STING (Stimulator of interferon genes protein), ERIS and MITA, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

UniProt: Q86WV6

Pathways: Activation of Innate immune Response