Der Kaninchen Polyklonal anti-TREM2 Antikörper (ABIN7871557) detektiert spezifisch TREM2 in WB, ELISA und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.
TREM2
Reaktivität: Maus
FACS
Wirt: Ratte
Monoclonal
78-18
PE
Applikationshinweise
Optimal dilution of the Trem2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Trem2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
TREM2
(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
Andere Bezeichnung
Trem2
Hintergrund
Triggering receptor expressed on myeloid cells 2 also known as TREM-2 is a protein that in humans is encoded by the TREM2 gene. This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.