TREM2 Antikörper (AA 1-100)

Produktnummer ABIN749678

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-TREM2 Antikörper wird verwendet zum Nachweis von TREM2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für TREM2 Antikörper (AA 1-100) (ABIN749678)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TREM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TREM2 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: TREM2 Polyclonal Antibody

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TREM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TREM2 Antikörper (ABIN749678)

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." in: Neurotoxicity research, (2021) (PubMed).

Rai, Dietz, Dilisio, Radwan, Agrawal: "Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswine." in: Arthritis research & therapy, Vol. 18, Issue 1, pp. 203, (2016) (PubMed).

Satoh, Kawana, Yamamoto, Ishida, Saito, Arima: "A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues." in: Alzheimer's research & therapy, Vol. 5, Issue 4, pp. 30, (2014) (PubMed).

Details zu TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Andere Bezeichnung: TREM2

Hintergrund:

Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM2

Background: May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

Gen-ID: 54209

UniProt: Q9NZC2