FKBP15 Antikörper (AA 19-1210)

Produktnummer ABIN7871554

Der Kaninchen Polyklonal anti-FKBP15 Antikörper (ABIN7871554) detektiert spezifisch FKBP15 in WB, ELISA, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für FKBP15 Antikörper (AA 19-1210) (ABIN7871554)

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-FKBP15 Antikörper

Bindungsspezifität: AA 19-1210

Verwendungszweck: FKBP15 Antibody / FKBP133

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A19-D1210) was used as the immunogen for the FKBP15 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FKBP15 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the FKBP15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Andere Bezeichnung: FKBP15

Hintergrund: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interaktom