FKBP15 Antikörper (AA 19-1210) (HRP)

Produktnummer ABIN7990958

Der HRP-konjugierte Kaninchen Polyklonal anti-FKBP15 Antikörper (ABIN7990958) detektiert spezifisch FKBP15 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für FKBP15 Antikörper (AA 19-1210) (HRP) (ABIN7990958)

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP15 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FKBP15 Antikörper (HRP)

Bindungsspezifität: AA 19-1210

Verwendungszweck: Anti-FKBP135/FKBP15 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FKBP135/FKBP15 recombinant protein (Position: A19-D1210).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Andere Bezeichnung: FKBP15

Hintergrund:

Background: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

Gene Full Name: FKBP prolyl isomerase family member 15

Gen-ID: 23307

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interaktom