Reelin Antikörper (AA 1796-2115)

Produktnummer ABIN7871363

Dieser Maus Monoklonal Antikörper detektiert spezifisch Reelin in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Reelin Antikörper (AA 1796-2115) (ABIN7871363)

Target: Reelin (RELN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Reelin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RELN-4498

Produktdetails anti-Reelin Antikörper

Bindungsspezifität: AA 1796-2115

Verwendungszweck: Reelin Antibody / RELN

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 1796-2115 was used as the immunogen for the Reelin antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Reelin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Reelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Reelin

Target: Reelin (RELN)

Andere Bezeichnung: Reelin

Hintergrund: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

UniProt: P78509

Pathways: Synaptic Membrane