Reelin Antikörper (N-Term)

Produktnummer ABIN6264693

Produktdetails anti-Reelin Antikörper

Target: Reelin (RELN)

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Reelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: RELN Antibody detects endogenous levels of total RELN.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RELN, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Reelin

Target: Reelin (RELN)

Andere Bezeichnung: RELN (RELN Produkte)

Synonyme: LIS2 antikoerper, PRO1598 antikoerper, RL antikoerper, reeler antikoerper, rl antikoerper, Reelen antikoerper, Rl antikoerper, reln antikoerper, RELN antikoerper, MGC172539 antikoerper, reelin antikoerper, reelin L homeolog antikoerper, RELN antikoerper, Reln antikoerper, reln antikoerper, reln.L antikoerper, LOC579060 antikoerper

Hintergrund:

Description: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Gene: RELN

Molekulargewicht: 388kDa

Gen-ID: 5649

UniProt: P78509

Pathways: Synaptic Membrane