Rekombinanter Villin 1 Antikörper (AA 179-311)

Produktnummer ABIN7871357

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Villin 1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Villin 1 Antikörper (AA 179-311) (ABIN7871357)

Target: Villin 1 (VIL1)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Villin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: VIL1-2310R

Produktdetails anti-Villin 1 Antikörper

Bindungsspezifität: AA 179-311

Verwendungszweck: Recombinant Villin Antibody / VIL1

Aufreinigung: Protein A affinity chromatography

Immunogen: Amino acids 179-311 from the human protein were used as the immunogen for this recombinant Villin antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the recombinant Villin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Villin 1

Target: Villin 1 (VIL1)

Andere Bezeichnung: Villin

Hintergrund: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization