LSP1 Antikörper (AA 174-278)

Produktnummer ABIN7871286

Der Maus Monoklonal anti-LSP1 Antikörper wird verwendet zum Nachweis von LSP1 in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für LSP1 Antikörper (AA 174-278) (ABIN7871286)

Target: LSP1 (Lymphocyte-Specific Protein 1 (LSP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LSP1 Antikörper ist unkonjugiert

Applikation: ELISA

Güteklasse: Carrier-free

Klon: LSP1-3042

Produktdetails anti-LSP1 Antikörper

Bindungsspezifität: AA 174-278

Verwendungszweck: LSP1 Antibody / Lymphocyte Specific Protein 1 (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 174-278) was used as the immunogen for this LSP1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LSP1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the LSP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu LSP1

Target: LSP1 (Lymphocyte-Specific Protein 1 (LSP1))

Andere Bezeichnung: LSP1

Hintergrund: LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.

UniProt: P33241