Flotillin 2 Antikörper (AA 169-344)

Produktnummer ABIN7871202

Der Maus Monoklonal anti-Flotillin 2 Antikörper wird verwendet zum Nachweis von Flotillin 2 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC (p) und IF.

Kurzübersicht für Flotillin 2 Antikörper (AA 169-344) (ABIN7871202)

Target: Flotillin 2 (FLOT2)

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Flotillin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: 4D8A3

Produktdetails anti-Flotillin 2 Antikörper

Bindungsspezifität: AA 169-344

Verwendungszweck: FLOT2 Antibody / Flotillin 2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K169-K344) was used as the immunogen for the FLOT2 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FLOT2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the FLOT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Flotillin 2

Target: Flotillin 2 (FLOT2)

Andere Bezeichnung: FLOT2

Hintergrund: FLOT2 (Flotillin 2), also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al. (1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the ESA cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al. (1997) found that mouse Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured mouse neuronal stem cells, Li et al. (2012) found that palmitoylation and oligomerization of flotillin-2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of flotillin-2 was not changed in Dhhc5 mutant neurons.

UniProt: Q14254