Cathepsin K Antikörper (AA 163-274)

Produktnummer ABIN7871124

Der Maus Monoklonal anti-Cathepsin K Antikörper wird verwendet zum Nachweis von Cathepsin K in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Cathepsin K Antikörper (AA 163-274) (ABIN7871124)

Target: Cathepsin K (CTSK)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin K Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CTSK-2792

Produktdetails anti-Cathepsin K Antikörper

Bindungsspezifität: AA 163-274

Verwendungszweck: Cathepsin K Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 163-274) was used as the immunogen for the Cathepsin K antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cathepsin K antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Cathepsin K antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: Cathepsin K

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades