TRIP4 Antikörper (AA 158-563)

Produktnummer ABIN7871028

Der Kaninchen Polyklonal anti-TRIP4 Antikörper wird verwendet zum Nachweis von TRIP4 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für TRIP4 Antikörper (AA 158-563) (ABIN7871028)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIP4 Antikörper

Bindungsspezifität: AA 158-563

Verwendungszweck: ASC1 Antibody / TRIP-4

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q158-D563) was used as the immunogen for the ASC1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ASC1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ASC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Andere Bezeichnung: ASC1

Hintergrund: Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene. This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).

UniProt: Q15650