TRIP4 Antikörper (AA 50-130)

Produktnummer ABIN7225944

Der Kaninchen Polyklonal anti-TRIP4 Antikörper wird verwendet zum Nachweis von TRIP4 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für TRIP4 Antikörper (AA 50-130) (ABIN7225944)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TRIP4 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-ASC-1 Polyclonal Antibody

Spezifität: ASC-1 Polyclonal Antibody detects endogenous levels of ASC-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ASC-1 at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Andere Bezeichnung: ASC-1

Hintergrund: TRIP4, Activating signal cointegrator 1, ASC-1, Thyroid receptor-interacting protein 4, TR-interacting protein 4, TRIP-4TRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in TRIP4 are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).

Molekulargewicht: 66kD

Gen-ID: 9325

UniProt: Q15650