NK2 Homeobox 5 Antikörper (AA 15-132)

Produktnummer ABIN7870781

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NK2 Homeobox 5 in WB, ELISA, IF, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NK2 Homeobox 5 Antikörper (AA 15-132) (ABIN7870781)

Target: NK2 Homeobox 5 (NKX2-5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-NK2 Homeobox 5 Antikörper

Bindungsspezifität: AA 15-132

Verwendungszweck: NKX2.5 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K15-R132) was used as the immunogen for the NKX2.5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NKX2.5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NKX2.5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: NKX2.5

Hintergrund: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 directly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development