Gephyrin Antikörper (AA 148-736)

Produktnummer ABIN7870771

Der Kaninchen Polyklonal anti-Gephyrin Antikörper (ABIN7870771) detektiert spezifisch Gephyrin in WB, ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für Gephyrin Antikörper (AA 148-736) (ABIN7870771)

Target: Gephyrin (GPHN)

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Gephyrin Antikörper

Bindungsspezifität: AA 148-736

Verwendungszweck: Gephyrin Antibody / GPHN

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K148-L736) was used as the immunogen for the Gephyrin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Gephyrin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Gephyrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: Gephyrin

Hintergrund: Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development