APCS Antikörper (AA 143-223)

Produktnummer ABIN7870697

Dieser Maus Monoklonal Antikörper detektiert spezifisch APCS in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APCS Antikörper (AA 143-223) (ABIN7870697)

Target: APCS (Amyloid P Component, Serum (APCS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APCS Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: APCS-3240

Produktdetails anti-APCS Antikörper

Bindungsspezifität: AA 143-223

Verwendungszweck: Serum Amyloid P Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 143-223) was used as the immunogen for the Serum Amyloid P antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Serum Amyloid P antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Serum Amyloid P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Andere Bezeichnung: Serum Amyloid P

Hintergrund: Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.

UniProt: P02743