ABCE1 Antikörper (AA 141-599)

Produktnummer ABIN7870676

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ABCE1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Zebrafisch (Danio rerio).

Kurzübersicht für ABCE1 Antikörper (AA 141-599) (ABIN7870676)

Target: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ABCE1 Antikörper

Bindungsspezifität: AA 141-599

Verwendungszweck: Zebrafish ATP binding cassette E1 Antibody / Abce1

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish ABCE1 recombinant protein (amino acids Q141-D599) was used as the immunogen for the Zebrafish ATP binding cassette E1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish ATP binding cassette E1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish ATP binding cassette E1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ABCE1

Target: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Andere Bezeichnung: ATP binding cassette E1

Hintergrund: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

UniProt: Q6TNW3