KNG1 Antikörper (AA 138-166)

Produktnummer ABIN7870583

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KNG1 in WB, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KNG1 Antikörper (AA 138-166) (ABIN7870583)

Target: KNG1 (Kininogen 1 (KNG1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-KNG1 Antikörper

Bindungsspezifität: AA 138-166

Verwendungszweck: KNG1 Antibody / Kininogen 1 / Bradykinin

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 138-166 from the human protein was used as the immunogen for the KNG1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the KNG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the KNG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: KNG1

Hintergrund: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process