STRADA Antikörper (AA 12-41)

Produktnummer ABIN7870293

Der Kaninchen Polyklonal anti-STRADA Antikörper wird verwendet zum Nachweis von STRADA in Proben von Human. Er wurde validiert für WB, IF und FACS.

Kurzübersicht für STRADA Antikörper (AA 12-41) (ABIN7870293)

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-STRADA Antikörper

Bindungsspezifität: AA 12-41

Verwendungszweck: LYK5 Antibody / STRADA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 12-41 from the human protein was used as the immunogen for the LYK5 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the LYK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the LYK5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu STRADA

Target: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Andere Bezeichnung: LYK5

Hintergrund: LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.

UniProt: Q7RTN6

Pathways: AMPK Signaling