ISL1 Antikörper (AA 118-161)

Produktnummer ABIN7870257

Der Kaninchen Polyklonal anti-ISL1 Antikörper wird verwendet zum Nachweis von ISL1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für ISL1 Antikörper (AA 118-161) (ABIN7870257)

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ISL1 Antikörper

Bindungsspezifität: AA 118-161

Verwendungszweck: Islet 1 Antibody / ISL1

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids D118-E161) was used as the immunogen for the Islet 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Islet 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Islet 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ISL1

Target: ISL1 (ISL LIM Homeobox 1 (ISL1))

Andere Bezeichnung: Islet 1

Hintergrund: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding