PDIA2 Antikörper (AA 117-492)

Produktnummer ABIN7870250

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDIA2 in ELISA, WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PDIA2 Antikörper (AA 117-492) (ABIN7870250)

Target: PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-PDIA2 Antikörper

Bindungsspezifität: AA 117-492

Verwendungszweck: PDIA2 Antibody / Protein disulfide-isomerase A2 / PDIp

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Y117-D492) was used as the immunogen for the PDIA2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDIA2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PDIA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PDIA2

Target: PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

Andere Bezeichnung: PDIA2

Hintergrund: Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.

UniProt: Q13087

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response