Rekombinanter Uroplakin 1B Antikörper (AA 109-229)

Produktnummer ABIN7870053

Der Kaninchen Monoklonal anti-Uroplakin 1B Antikörper wird verwendet zum Nachweis von Uroplakin 1B in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter Uroplakin 1B Antikörper (AA 109-229) (ABIN7870053)

Target: Uroplakin 1B (UPK1B)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Uroplakin 1B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: UPK1B-8976R

Produktdetails anti-Uroplakin 1B Antikörper

Bindungsspezifität: AA 109-229

Verwendungszweck: UPK1B Antibody / Uroplakin 1B

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 109-229) from the human protein was used as the immunogen for the UPK1B antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the UPK1B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the UPK1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Andere Bezeichnung: UPK1B

Hintergrund: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

UniProt: O75841