Uroplakin 1B Antikörper (AA 109-229)

Produktnummer ABIN7870045

Der Maus Monoklonal anti-Uroplakin 1B Antikörper (Klon UPK1B-3273) (ABIN7870045) detektiert spezifisch Uroplakin 1B in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Uroplakin 1B Antikörper (AA 109-229) (ABIN7870045)

Target: Uroplakin 1B (UPK1B)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Uroplakin 1B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: UPK1B-3273

Produktdetails anti-Uroplakin 1B Antikörper

Bindungsspezifität: AA 109-229

Verwendungszweck: Uroplakin 1B Antibody / UPK1B

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this Uroplakin 1B antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Uroplakin 1B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Uroplakin 1B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Andere Bezeichnung: Uroplakin 1B

Hintergrund: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

UniProt: O75841