VEGFC Antikörper (AA 108-223)

Produktnummer ABIN7870024

Der Kaninchen Polyklonal anti-VEGFC Antikörper (ABIN7870024) detektiert spezifisch VEGFC in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für VEGFC Antikörper (AA 108-223) (ABIN7870024)

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGFC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-VEGFC Antikörper

Bindungsspezifität: AA 108-223

Verwendungszweck: Vegfc Antibody / Vascular endothelial growth factor C

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived mouse recombinant protein (A108-R223) was used as the immunogen for the Vegfc antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Vegfc antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Vegfc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Andere Bezeichnung: Vegfc

Hintergrund: Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation, positive regulation of angiogenesis, and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, positive regulation of lymphangiogenesis, and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery, brain, cardiovascular system, embryo mesenchyme, and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C).

UniProt: P97953

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2