CBS Antikörper (AA 102-342)

Produktnummer ABIN7869913

Der Kaninchen Polyklonal anti-CBS Antikörper (ABIN7869913) detektiert spezifisch CBS in WB, ELISA, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CBS Antikörper (AA 102-342) (ABIN7869913)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-CBS Antikörper

Bindungsspezifität: AA 102-342

Verwendungszweck: CBS Antibody / Cystathionine Beta Synthase

Aufreinigung: Antigen affinity purified

Immunogen: A human recombinant partial protein (amino acids K102-E342) was used as the immunogen for the CBS antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CBS antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CBS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Andere Bezeichnung: CBS

Hintergrund: CBS (Cystathionine Beta Synthase) is a pyridoxal-5'-phosphate-dependent enzyme that plays a central role in the transsulfuration pathway. It catalyzes the condensation of serine and homocysteine to form cystathionine, an essential step in the synthesis of cysteine. This pathway is critical for maintaining sulfur amino acid metabolism, redox balance, and cellular homeostasis. A CBS antibody is commonly used in research focused on amino acid metabolism and associated disorders.

In addition to its role in cysteine biosynthesis, CBS activity contributes to the regulation of homocysteine levels. Elevated homocysteine is a known risk factor for cardiovascular disease, stroke, and neurodegeneration. Mutations in the CBS gene are responsible for homocystinuria, a metabolic disorder characterized by abnormal accumulation of homocysteine, highlighting the enzyme’s clinical significance. Researchers employ a CBS antibody to study enzyme expression and function in metabolic pathways and disease models.

CBS is also involved in producing hydrogen sulfide (H2S), a gaseous signaling molecule with important roles in vascular function, neuromodulation, and cytoprotection. Dysregulated H2S production has been associated with cancer, hypertension, and neurological disease. Investigating CBS with a CBS antibody allows researchers to better understand its enzymatic versatility and its impact on multiple signaling networks.

NSJ Bioreagents offers a high-quality CBS antibody validated for applications such as western blot, immunohistochemistry, and immunoprecipitation. Selecting a CBS antibody from NSJ Bioreagents ensures reliable detection and reproducible results in studies of sulfur metabolism, homocysteine regulation, and disease biology.

UniProt: P35520