Amphiregulin Antikörper (AA 101-180)

Produktnummer ABIN7869891

Der Kaninchen Polyklonal anti-Amphiregulin Antikörper wird verwendet zum Nachweis von Amphiregulin in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für Amphiregulin Antikörper (AA 101-180) (ABIN7869891)

Target: Amphiregulin (AREG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Amphiregulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Amphiregulin Antikörper

Bindungsspezifität: AA 101-180

Verwendungszweck: AREG Antibody / Amphiregulin

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S101-R180) was used as the immunogen for the AREG antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AREG antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the AREG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Amphiregulin

Target: Amphiregulin (AREG)

Andere Bezeichnung: AREG

Hintergrund: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

UniProt: P15514

Pathways: RTK Signalweg, EGFR Signaling Pathway