PKC iota Antikörper (AA 100-300)
Kurzübersicht für PKC iota Antikörper (AA 100-300) (ABIN7869854)
Target
Alle PKC iota (PRKCI) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
-
-
Bindungsspezifität
- AA 100-300
-
Verwendungszweck
- PRKCI Antibody / PKC iota (azide and preservative free)
-
Aufreinigung
- Protein A/G affinity
-
Immunogen
- A portion of amino acids 100-300 was used as the immunogen for the PRKCI antibody.
-
Isotyp
- IgG2b, kappa
-
-
-
-
Applikationshinweise
- Optimal dilution of the PRKCI antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Konservierungsmittel
- Azide free
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the PRKCI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
-
Andere Bezeichnung
- PRKCI
-
Hintergrund
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC i 1/2L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
-
UniProt
- P41743
-
Pathways
- Neurotrophin Signalübertragung, Cell-Cell Junction Organization, Tube Formation
Target
-